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Ten Commandments of "The New Therapeutics"

20 Jan

By Gary Schwitzer

Sometimes I blog things that I see just to ensure that I have a place
to keep them.  This is one of those times. Because this is a keeper.
The Carlat Psychiatry Blog re-posted a list written by John Yudkin and posted by BMJ blogger Richard Lehman – Ten Commandments for excellent clinical practice.
The New Therapeutics: Ten Commandments

  • Thou shalt treat according to level of risk rather than level of risk factor.
  • Thou shalt exercise caution when adding drugs to existing polypharmacy.
  • Thou shalt consider benefits of drugs as proven only by hard endpoint studies.
  • Thou shalt not bow down to surrogate endpoints, for these are but graven images.
  • Thou shalt not worship Treatment Targets, for these are but the creations of Committees.
  • Thou shalt apply a pinch of salt to Relative Risk Reductions,
    regardless of P values, for the population of their provenance may bear
    little relationship to thy daily clientele.
  • Thou shalt honour the Numbers Needed to Treat, for therein rest the
    clues to patient-relevant information and to treatment costs.
  • Thou shalt not see detailmen, nor covet an Educational Symposium in a luxury setting.
  • Thou shalt share decisions on treatment options with the patient in
    the light of estimates of the individual’s likely risks and benefits.
  • Honour the elderly patient, for although this is where the greatest
    levels of risk reside, so do the greatest hazards of many treatments.

Amen.
Time for a little of that religion.

Please also note that Alice Dreger posted a laymen’s explanation of the “Ten Commandments” for those who may not be aware of some of the
terminology.

 
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